{"id":974,"date":"2020-08-19T18:07:30","date_gmt":"2020-08-20T01:07:30","guid":{"rendered":"http:\/\/northislandurology.ca\/?page_id=974"},"modified":"2020-08-19T18:20:02","modified_gmt":"2020-08-20T01:20:02","slug":"trimix-intracavernosal-injection","status":"publish","type":"page","link":"https:\/\/northislandurology.ca\/procedures\/erectile-dysfunction\/trimix-intracavernosal-injection\/","title":{"rendered":"Trimix Intracavernosal Injection"},"content":{"rendered":"<div class=\"vce-row-container\"><div class=\"vce-row vce-row--col-gap-30 content-column vce-row-columns--top vce-row-content--top\" id=\"el-58c564e8\" data-vce-do-apply=\"all el-58c564e8\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-3-05p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-60c9358a\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-60c9358a\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-60c9358a\"><\/div><\/div><\/div><div class=\"vce-col vce-col--md-95-34p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-cec7e435\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-cec7e435\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-cec7e435\"><div class=\"vce-row-container\"><div class=\"vce-row vce-row--col-gap-30 vce-row-wrap--reverse vce-row-columns--top vce-row-content--top\" id=\"el-d53f431d\" data-vce-do-apply=\"all el-d53f431d\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-2-3 vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-693e037b\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-693e037b\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-693e037b\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-df47b790\" data-vce-do-apply=\"all el-df47b790\"><p>Trimix intracavernosal injection is a combination of medications used for erectile dysfunction. These medications are injected directly into the side of the penis.<\/p><p>Trimix is a combination of 3 separate medications<\/p><ul><li>Papaverine<\/li><li>Alprostadil<\/li><li>Phentolamine<\/li><\/ul><p><strong>Risks of Intracavernosal Injections:<\/strong><\/p><ul><li>Pain<\/li><li>Bleeding<\/li><li>Bruising<\/li><li>Priapism (see below)<\/li><\/ul><p>Trimix should be stored in the refrigerator and away from light.<\/p><p><strong>How to Inject<\/strong><\/p><ol><li>Gather your supplies.<ul><li>Medication vial<\/li><li>1 syringe<\/li><li>2 alcohol wipes<\/li><li>Sharps container<\/li><\/ul><\/li><li>Wash your hands.<\/li><li>Wipe the top of the medication vial with an alcohol swab.<\/li><li>Remove the cap from the needle on the syringe. Make sure that the needle does not come into contact with anything other than the medication vial.<\/li><li>Withdraw air into the syringe. You want to withdraw approximately the same volume of air which you are going to be withdrawing from the vial.<\/li><li>Insert the needle into the plastic stopper on the top of the medication vial. Push down on the stopper to inject the air into the vial.<\/li><li>Turn the vial upside down and withdraw the correct amount of fluid (see below for correct dosage titration). You may need to withdraw more fluid initially to help clear out the air bubbles.<\/li><li>Once you have the correct dose, withdraw the needle from the vial.<\/li><li>Find a comfortable position either laying down or sitting.<\/li><li>Grasp the head of your penis, and pull it out on stretch.<\/li><li>Locate the area of your penis where you plan to inject. If you imagine your penis like a clock, you want to avoid 6 o\u2019clock and 12 o\u2019clock.<\/li><li>Aim to inject either at 3 o\u2019clock or 9 o\u2019clock.<\/li><li>Wipe the planned injection site with the alcohol swab.<\/li><li>With the penis on stretch, insert the needle all the way into the erectile tissue of the penis.<\/li><li>With the needle in position, push down on the syringe quickly. DO NOT move the needle while you are injecting.<\/li><li>Once you have injected the medication, remove the needle and place pressure on the site for 2-3 minutes to prevent bruising.<\/li><li>Place the syringe in the sharps container.<\/li><\/ol><p><strong>Finding the Correct Dose<\/strong><\/p><p>This is a very important aspect of trimix injection teaching. Your urologist will give you an initial dose of the medication to start with. You will also be instructed how to titrate up the dose of your medication.<\/p><p><strong>Important Information<\/strong><\/p><ul><li>DO NOT take more medication than prescribed<\/li><li>DO NOT use more than 1 injection in 24 hours<\/li><li>DO NOT give yourself another injection if the medication dose does not work<\/li><li>You can inject up to 3 times per week, as long as there is more than 24 hours between doses.<\/li><\/ul><p><strong>Please refer to the erection scale below<\/strong><\/p><\/div><\/div><div class=\"vce-row-container\"><div class=\"vce-row vce-row--col-gap-30 vce-row-columns--top vce-row-content--top\" id=\"el-442035a8\" data-vce-do-apply=\"all el-442035a8\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-cd028ba4\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-cd028ba4\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-cd028ba4\"><div class=\"vce-single-image-container vce-single-image--align-left\"><div class=\"vce vce-single-image-wrapper\" id=\"el-bf0857b4\" data-vce-do-apply=\"all el-bf0857b4\"><figure><div class=\"vce-single-image-inner vce-single-image--absolute\" style=\"padding-bottom: 16.6324%; width: 974px;\"><img class=\"vce-single-image\" width=\"974\" height=\"162\"src=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_TrimixInjectionDosingChart-974x162.png\" srcset=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_TrimixInjectionDosingChart-320x53.png 320w,https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_TrimixInjectionDosingChart-480x80.png 480w,https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_TrimixInjectionDosingChart-800x133.png 800w,https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_TrimixInjectionDosingChart-974x162.png 974w\" data-img-src=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/04\/ErectileDysfunction_TrimixInjectionDosingChart.png\" alt=\"\" title=\"Trimix Injection Dosing Chart\"\/><\/div><\/figure><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-a19d6e86\" data-vce-do-apply=\"all el-a19d6e86\"><p><em><strong>Example<\/strong><\/em><\/p><ul><li><em>Joe was given his first dose in the clinic of 0.1 mL (10 units). This gave him an erection of 2\/10.<\/em><\/li><li><em>Joe was instructed to increase his dose by 0.1 mL per treatment.<\/em><\/li><li><em>His second injection was 0.2 mL (20 units). This gave him an erection of 4\/10.<\/em><\/li><li><em>Joe\u2019s third injection was 0.3 mL (30 units). This gave him an erection of 7\/10.<\/em><\/li><li><em>Joe\u2019s fourth injection was 0.4 mL (40 units). This resulted in a 10\/10 erection.<\/em><\/li><li><em>Joe\u2019s dose for his trimix is 0.4 mL (40 units). He should continue to use this dose in the future.<\/em><\/li><\/ul><p><strong>What happens if my erection won\u2019t go away?<\/strong><\/p><p>This is called priapism, or an erection that lasts too long.<\/p><p>The pharmacy will provide you with a medication to try and counteract the trimix therapy. This is called pseudoephedrine HCl. If your erection is firm and lasts &gt;3 hours, you should take 4 (30 mg) tablets of pseudoephedrine.<\/p><p>If your erection lasts more than 4 hours, you need to be seen at the emergency department. This is an emergency. Tell the emergency room staff that you have had an erection lasting more than 4 hours and that you have used trimix injection therapy. You will be seen on an urgent basis.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-1-3 vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-8e052211\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-8e052211\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-8e052211\"><div class=\"vce-single-image-container vce-single-image--align-center\"><div class=\"vce vce-single-image-wrapper\" id=\"el-76877a1b\" data-vce-do-apply=\"all el-76877a1b\"><figure><div class=\"vce-single-image-inner vce-single-image--absolute\" style=\"padding-bottom: 115.83%; width: 259px;\"><img class=\"vce-single-image\" width=\"259\" height=\"300\"src=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_IntracarvernosalInjection-259x300.jpg\" srcset=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/08\/ErectileDysfunction_IntracarvernosalInjection-259x300.jpg 259w\" data-img-src=\"https:\/\/northislandurology.ca\/wp-content\/uploads\/2020\/04\/ErectileDysfunction_IntracarvernosalInjection.jpg\" alt=\"\" title=\"Intracarvernosal Injection\"\/><\/div><\/figure><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-5p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-48d9cad2\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-48d9cad2\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-48d9cad2\"><\/div><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"Trimix intracavernosal injection is a combination of medications used for erectile dysfunction. These medications are injected directly into the side of the penis.Trimix is a combination of 3 separate medicationsPapaverineAlprostadilPhentolamineRisks of Intracavernosal Injections:PainBleedingBruisingPriapism (see below)Trimix should be stored in the refrigerator and away from light.How to InjectGather your supplies.Medication vial1 syringe2 alcohol wipesSharps containerWash your&#8230; <a class=\"view-article\" href=\"https:\/\/northislandurology.ca\/procedures\/erectile-dysfunction\/trimix-intracavernosal-injection\/\">View Article<\/a>","protected":false},"author":1,"featured_media":0,"parent":907,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"footnotes":""},"_links":{"self":[{"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/pages\/974"}],"collection":[{"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/comments?post=974"}],"version-history":[{"count":3,"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/pages\/974\/revisions"}],"predecessor-version":[{"id":977,"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/pages\/974\/revisions\/977"}],"up":[{"embeddable":true,"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/pages\/907"}],"wp:attachment":[{"href":"https:\/\/northislandurology.ca\/wp-json\/wp\/v2\/media?parent=974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}